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你正在浏览JOURNAL OF INORGANIC BIOCHEMISTRY期刊下所有文献
  • DNA-binding and in vitro cytotoxic activity of platinum(II) complexes of curcumin and caffeine.

    abstract：:Three Pt(II) complexes containing the natural ligands curcumin and caffeine, namely [Pt(curc)(PPh3)2]Cl (1), [PtCl(curc)(DMSO)] (2) (curc = deprotonated curcumin) and trans-[Pt(caffeine)Cl2(DMSO)] (3), were synthesized and fully characterized. The data obtained suggest that, for both 1 and 2, the anion of curcumin is ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.110749

    authors： Censi V,Caballero AB,Pérez-Hernández M,Soto-Cerrato V,Korrodi-Gregório L,Pérez-Tomás R,Dell'Anna MM,Mastrorilli P,Gamez P

    更新日期：2019-09-01 00:00:00

  • Catalase prevents myeloperoxidase self-destruction in response to oxidative stress.

    abstract：:Catalase (CAT) and myeloperoxiase (MPO) are heme-containing enzymes that have attracted attention for their role in the etiology of numerous respiratory disorders such as cystic fibrosis, bronchial asthma, and acute hypoxemic respiratory failure. However, information regarding the interrelationship and competition bet...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.110706

    authors： Ali I,Khan SN,Chatzicharalampous C,Bai D,Abu-Soud HM

    更新日期：2019-08-01 00:00:00

  • Inhibition of Na+/K+- and Ca2+-ATPase activities by phosphotetradecavanadate.

    abstract：:Polyoxometalates (POMs) are promising inorganic inhibitors for P-type ATPases. The experimental models used to study the effects of POMs on these ATPases are usually in vitro models using vesicles from several membrane sources. Very recently, some polyoxotungstates, such as the Dawson anion [P2W18O62]6-, were shown to...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.110700

    authors： Fraqueza G,Fuentes J,Krivosudský L,Dutta S,Mal SS,Roller A,Giester G,Rompel A,Aureliano M

    更新日期：2019-08-01 00:00:00

  • Design, synthesis, and evaluation of phosphorescent Ir(III) complexes with anticancer activity.

    abstract：:A range of phosphorescent Ir(III) complexes containing four diverse P^P-chelating ligands of the type [Ir(ppy)2(L)][PF6], (ppy = 2‑phenylpyridine) where L is 1,2‑bis(diphenylphosphino)benzene (L1), 1,2‑bis(diphenylphosphino)ethane (L2), 1,2‑bis(diphenylphosphino)propane(L3) and 1,8‑bis(diphenylphosphino)naphthalene (L...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.110703

    authors： Liu Z,Li J,Ge X,Zhang S,Xu Z,Gao W

    更新日期：2019-08-01 00:00:00

  • Vanadocene complexes bearing N,N'-chelating ligands: Synthesis, structures and in vitro cytotoxic studies on the A549 lung adenocarcinoma cell line.

    abstract：:Ten new vanadocene complexes bearing N,N'-chelating ligands were prepared, characterized, and their cytotoxicity toward a panel of cancer cells was measured. Structures of four vanadocene compounds were determined by single crystal X-ray diffraction analysis. Complexes containing 1,2-bis(phenylimino)acenaphthene (bian...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.03.015

    authors： Melounková L,Machálková A,Havelek R,Honzíček J,Řezáčová M,Císařová I,Peterová E,Vinklárek J

    更新日期：2019-06-01 00:00:00

  • Stability constant determination of sulfur and selenium amino acids with Cu(II) and Fe(II).

    abstract：:Sulfur- and selenium-containing amino acids are of great biological importance, but their metal-binding properties with biologically-relevant metal ions are not well investigated. Stability constants of the methionine, selenomethionine, methylcysteine, and methylselenocysteine with Cu(II) and Fe(II) were determined by...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.03.001

    authors： Murphy JM,Gaertner AAE,Williams T,McMillen CD,Powell BA,Brumaghim JL

    更新日期：2019-06-01 00:00:00

  • The crystal structure of the CopC protein from Pseudomonas fluorescens reveals amended classifications for the CopC protein family.

    abstract：:The bacterial CopC family of proteins are periplasmic copper binding proteins that act in copper detoxification. These proteins contain Cu(I) and/or Cu(II) binding sites, with the family that binds Cu(II) only the most prevalent, based on sequence analyses. Here we present three crystal structures of the CopC protein ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.03.007

    authors： Udagedara SR,Wijekoon CJK,Xiao Z,Wedd AG,Maher MJ

    更新日期：2019-06-01 00:00:00

  • Anticancer activity and mechanism of bis-pyrimidine based dimetallic Ru(II)(η6-p-cymene) complex in human non-small cell lung cancer via p53-dependent pathway.

    abstract：:Non-small cell lung cancer (NSCLC) is the most common cancer worldwide, which is related with poor prognosis and resistance to chemotherapy. Notably, ruthenium-based complexes have emerged as good alternative to the currently used platinum-based drugs for cancer therapy. In the present study, we synthesized a novel bi...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.01.019

    authors： Bhatti MZ,Ali A,Duong HQ,Chen J,Rahman FU

    更新日期：2019-05-01 00:00:00

  • Palladium(II) complexes with salicylaldehyde ligands: Synthesis, characterization, structure, in vitro and in silico study of the interaction with calf-thymus DNA and albumins.

    abstract：:The synthesis and characterization of four palladium(II) complexes with substituted salicylaldehydes (X-saloH) having the general formula [Pd(X-salo)2] was undertaken. The complexes are formulated as [Pd(3-OCH3-salo)2] 1, [Pd(5-NO2-salo)2] 2, [Pd(5-Cl-salo)2] 3, and [Pd(5-Br-salo)2] 4. The structure of complex 1 was v...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.02.013

    authors： Zianna A,Geromichalos GD,Hatzidimitriou AG,Coutouli-Argyropoulou E,Lalia-Kantouri M,Psomas G

    更新日期：2019-05-01 00:00:00

  • Ru(II)/N-N/PPh3 complexes as potential anticancer agents against MDA-MB-231 cancer cells (N-N = diimine or diamine).

    abstract：:The rational design of anticancer agents that acts in specific biological targets is one of the most effective strategies for developing chemotherapeutic agents. Aiming at obtaining new ruthenium (II) compounds with good cytotoxicity against tumor cells, a series of new complexes of general formula [RuCl(PPh3)(Hdpa)(N...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.01.006

    authors： Ribeiro GH,Colina-Vegas L,Clavijo JCT,Ellena J,Cominetti MR,Batista AA

    更新日期：2019-04-01 00:00:00

  • An in vitro study on dentin demineralization and remineralization: Collagen rearrangements and influence on the enucleated phase.

    abstract：:Dentin remineralization is of clinical relevance in the therapy of caries and dentin hypersensitivity. This study is aimed at gaining more insights on a molecular scale, through IR spectroscopy, into dentin demineralization and remineralization. The dentin demineralization by ethylenediaminetetraacetic acid, EDTA (17%...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2019.01.004

    authors： Di Foggia M,Prati C,Gandolfi MG,Taddei P

    更新日期：2019-04-01 00:00:00

  • ZraP, the most prominent zinc protein under zinc stress conditions has no direct role in in-vivo zinc tolerance in Escherichia coli.

    abstract：:Escherichia coli ZraP (zinc resistance associated protein) is the major Zn containing soluble protein under Zn stress conditions. ZraP is the accessory protein of a bacterial two-component, Zn2+ sensitive signal transduction system ZraSR. ZraP has also been reported to act as a Zn2+ dependent molecular chaperone. An e...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.12.013

    authors： van der Weel L,As KS,Dekker WJC,van den Eijnden L,van Helmond W,Schiphorst C,Hagen WR,Hagedoorn PL

    更新日期：2019-03-01 00:00:00

  • In vitro anti-bacterial and time kill evaluation of binuclear tricyclohexylphosphanesilver(I) dithiocarbamates, {Cy3PAg(S2CNRR')}2.

    abstract：:Four binuclear phosphanesilver(I) dithiocarbamates, {cyclohexyl3PAg(S2CNRR')}2 for R = R' = Et (1), CH2CH2 (2), CH2CH2OH (3) and R = Me, R' = CH2CH2OH (4) have been synthesised and characterised by spectroscopy and crystallography, and feature tri-connective, μ2-bridging dithiocarbamate ligands and distorted tetrahedr...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.12.017

    authors： Tan YJ,Tan YS,Yeo CI,Chew J,Tiekink ERT

    更新日期：2019-03-01 00:00:00

  • Synthesis, characterization, DNA binding, topoisomerase I inhibition and antiproliferation activities of three new functionalized terpyridine platinum(II) complexes.

    abstract：:Three new platinum(II) complexes with pendent morpholine were synthesized, namely complex 1 ([Pt(L)Cl]CF3SO3), complex 2 ([Pt(L)(NH3)](CF3SO3)2) and complex 3 ([Pt(L)(PPh3)](CF3SO3)2), where L = 4'-[4-(4-morpholinobutyloxy)phenyl]-2,2':6',2″-terpyridine and PPh3 = triphenylphosphine. The detailed molecular structures ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.12.003

    authors： Chai K,Kuang W,Lan Z,Zhang L,Jiang Y,Han T,Niu J,Wang J,Duan X

    更新日期：2019-03-01 00:00:00

  • A ruthenium(II) complex containing a p-cresol group induces apoptosis in human cervical carcinoma cells through endoplasmic reticulum stress and reactive oxygen species production.

    abstract：:The chemical structures of Ru (II) complexes are known to affect their cellular behavior and toxicity. In this study, three new luminescent Ru (II) complexes, [Ru(bpy)2(HIPMP)](ClO4)2 (Ru1, bpy = 2,2'-bipyridine, HIPMP = 2-(1H-imidazo-[4,5-f] [1,10] phenanthrolin-2-yl)-4-methylphenol), [Ru(phen)2(HIPMP)](ClO4)2 (Ru2, ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.11.015

    authors： Xu L,Zhang PP,Fang XQ,Liu Y,Wang JQ,Zhou HZ,Chen ST,Chao H

    更新日期：2019-02-01 00:00:00

  • Synthesis and biological evaluation of biotin-conjugated anticancer thiosemicarbazones and their iron(III) and copper(II) complexes.

    abstract：:Triapine, the most prominent anticancer drug candidate from the substance class of thiosemicarbazones, was investigated in >30 clinical phase I and II studies. However, the results were rather disappointing against solid tumors, which can be explained (at least partially) due to inefficient delivery to the tumor site....

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.10.006

    authors： Kallus S,Uhlik L,van Schoonhoven S,Pelivan K,Berger W,Enyedy ÉA,Hofmann T,Heffeter P,Kowol CR,Keppler BK

    更新日期：2019-01-01 00:00:00

  • Zeise's salt as powerful platinating agent for proteins investigated by top-down-mass spectrometry.

    abstract：:Metallodrugs have become an integral part of modern medicinal chemistry with platinum drugs as anti-cancer agents being well-known examples. The historically interesting compound Zeise's salt, potassium trichlorido(ethene)platinate(II) has scarcely been investigated in this context yet. This study is geared towards sh...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.09.003

    authors： Cziferszky M,Gust R

    更新日期：2018-12-01 00:00:00

  • Copper(II) complexes with Fusobacterium nucleatum adhesin FadA: Coordination pattern, physicochemical properties and reactivity.

    abstract：:Fusobacterium nucleatum is an anaerobic, Gram-negative bacteria linked to colon cancer. It is interesting to determine how metal ions interact with bacterial adhesin proteins. To this end, the coordination of ATDAAS-NH2 and MKKFL-NH2 fragments of Fusobacterium adhesin A (FadA) to copper(II) ions was studied by potenti...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.09.012

    authors： Krupa K,Lesiów M,Stokowa-Sołtys K,Starosta R,Ptaszyńska N,Łęgowska A,Rolka K,Wernecki M,Cal M,Jeżowska-Bojczuk M

    更新日期：2018-12-01 00:00:00

  • Vanadyl complexes discriminate between neuroblastoma cells and primary neurons by inducing cell-specific apoptotic pathways.

    abstract：:Vanadium compounds have arisen as potential therapeutic agent for the treatment of cancers over the past decades. A few studies suggested that vanadyl complexes may discriminate between the cancerous and the normal cells. Here, we reported the investigation on the pro-apoptotic effect and the underlying mechanism of b...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.08.005

    authors： Zhang Y,Wang L,Zeng K,Wang K,Yang X

    更新日期：2018-11-01 00:00:00

  • Copper(II) diclofenac complexes: Synthesis, structural studies and interaction with albumins and calf-thymus DNA.

    abstract：:The reaction of the copper(II) diclofenac complex [Cu(dicl)2(H2O)2] (1) (dicl = deprotonated diclofenac (Hdicl)) with the chelating N-donor ligands ethylenediamine (en), propan-1,3-diamine (pn), unsymmetrical dimethylethylene-diamine (unsym-dmen) and N,N,N',N'-tetramethylethylene-diamine (temed) in methanol-water (4:1...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.07.009

    authors： Kumar S,Sharma RP,Venugopalan P,Ferretti V,Perontsis S,Psomas G

    更新日期：2018-10-01 00:00:00

  • Future perception in P450 research.

    abstract：:Cytochrome P450 (P450) of eukaryotes and prokaryotes diversified remarkably during the long course of their evolution. Since the diversification of P450 was the consequence of the adaptation of various living organisms to diverse environmental changes, the catalytic activities and physiological functions of the P450s ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.06.002

    authors： Omura T

    更新日期：2018-09-01 00:00:00

  • Synthesis and biological characterization of organoruthenium complexes with 8-hydroxyquinolines.

    abstract：:In this study we report the synthesis, characterization and a thorough biological evaluation of twelve organoruthenium-8-hydroxyquinolinato (Ru-hq) complexes. The chosen hqH ligands bear various halogen atoms in different positions which enables to study effect of the substituents on physico-chemical and biological pr...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.05.009

    authors： Kljun J,León IE,Peršič Š,Cadavid-Vargas JF,Etcheverry SB,He W,Bai Y,Turel I

    更新日期：2018-09-01 00:00:00

  • Cross-linked cytochrome P450 BM3 aggregates promoted by Ru(II)-diimine complexes bearing aldehyde groups.

    abstract：:Cross-linked enzyme aggregate (CLEA) methodology has been applied to immobilize cytochrome P450 BM3 variants (F87A and 21B3) with peroxygenase activity. Several Ru(II)-diimine complexes were found to be suitable cross-linking agents, surpassing the traditional glutaraldehyde and dextran aldehyde. They offer modular nu...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.06.001

    authors： Do MQ,Henry E,Kato M,Cheruzel L

    更新日期：2018-09-01 00:00:00

  • In-vivo evaluation of the response of Galleria mellonella larvae to novel copper(II) phenanthroline-phenazine complexes.

    abstract：:Herein we report the in-vivo characterisation and metabolic changes in Galleria mellonella larvae to a series of bis-chelate copper(II) phenanthroline-phenazine cationic complexes of [Cu(phen)2]2+ (Cu-Phen), [Cu(DPQ)(Phen)]2+ (Cu-DPQ-Phen) and [Cu(DPPZ)(Phen)]2+ (Cu-DPPZ-Phen) (where phen = 1,10-phenanthroline, DPQ = ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.05.020

    authors： Rochford G,Molphy Z,Browne N,Surlis C,Devereux M,McCann M,Kellett A,Howe O,Kavanagh K

    更新日期：2018-09-01 00:00:00

  • Synthetic investigation of binary-ternary Cr(III)-hydroxycarboxylic acid-aromatic chelator systems. Structure-specific influence on adipogenic biomarkers linked to insulin mimesis.

    abstract：:In an attempt to understand the aqueous interactions of Cr(III) with low-molecular mass physiological ligands and examine its role as an adipogenic metallodrug agent in Diabetes mellitus II, the pH-specific synthesis in the binary-ternary Cr(III)-(HA = hydroxycarboxylic acid)-(N,N)-aromatic chelator (AC) (HA = 2-hydro...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.02.001

    authors： Tsave O,Gabriel C,Kafantari M,Yavropoulou M,Yovos JG,Raptopoulou CP,Psycharis V,Terzis A,Mateescu C,Salifoglou A

    更新日期：2018-07-01 00:00:00

  • Conserved cysteine residues are necessary for nickel-induced allosteric regulation of the metalloregulatory protein YqjI (NfeR) in E. coli.

    abstract：:Transition metal homeostasis is necessary to sustain life. First row transition metals act as cofactors within the cell, performing vital functions ranging from DNA repair to respiration. However, intracellular metal concentrations exceeding physiological requirements may be toxic. In E. coli, the YqjH flavoprotein is...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.04.016

    authors： Blahut M,Dzul S,Wang S,Kandegedara A,Grossoehme NE,Stemmler T,Outten FW

    更新日期：2018-07-01 00:00:00

  • Biological evaluation of water soluble arene Ru(II) enantiomers with amino-oxime ligands.

    abstract：:New water soluble, enantiopure arene ruthenium compound SRuSN-(1R,4S)-[(η6-p-cymene)Ru{ĸNH(Bn),ĸNOH}Cl]Cl (Bn = benzyl, 1a') has been synthesized. The novel compound along with that previously described RRuRN-(1S,4R)-[(η6-p-cymene)Ru{ĸNH(Bn),ĸNOH}Cl]Cl (1a) was evaluated by polarimetry, ultra-violet and circular dichr...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.02.018

    authors： de la Cueva-Alique I,Sierra S,Muñoz-Moreno L,Pérez-Redondo A,Bajo AM,Marzo I,Gude L,Cuenca T,Royo E

    更新日期：2018-06-01 00:00:00

  • Effect of redox partner binding on CYP101D1 conformational dynamics.

    abstract：:We have compared the thermodynamics of substrate and redox partner binding of P450cam to its close homologue, CYP101D1, using isothermal titration calorimetry (ITC). CYP101D1 binds camphor about 10-fold more weakly than P450cam which is consistent with the inability of camphor to cause a complete low- to high-spin shi...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.02.013

    authors： Batabyal D,Poulos TL

    更新日期：2018-06-01 00:00:00

  • Development of a novel carboplatin like cytoplasmic trackable near infrared fluorophore conjugate via strain-promoted azide alkyne cycloaddition.

    abstract：:The successful design and pre-clicked synthesis of a non-toxic and cytosol trackable carboplatin-like near infrared fluorophore conjugate via strain-promoted azide alkyne cycloaddition (SPAAC) is reported. Reaction of cis-[Pt(2-azidopropane-1,3-diamine)(cbdca)] (cbdca = cyclobutane-1,1-dicarboxylato) and a bicyclo[6.1...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.02.010

    authors： Kitteringham E,Wu D,Cheung S,Twamley B,O'Shea DF,Griffith DM

    更新日期：2018-05-01 00:00:00

  • Bioactive ruthenium(II)-arene complexes containing modified 18β-glycyrrhetinic acid ligands.

    abstract：:Metal-arene complexes containing bioactive natural-product derived ligands can have new and unusual properties. We report the synthesis, characterization and antiproliferative activity of two new Ru(II) arene complexes with imidazole (dichlorido complex 1) or bipyridyl (chlorido complex 2) ligands conjugated to 18β-gl...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.02.004

    authors： Kong Y,Chen F,Su Z,Qian Y,Wang FX,Wang X,Zhao J,Mao ZW,Liu HK

    更新日期：2018-05-01 00:00:00

  • Cognitive dysfunction associated with aluminum hydroxide-induced macrophagic myofasciitis: A reappraisal of neuropsychological profile.

    abstract：:Patients with macrophagic myofasciitis (MMF) present with diffuse arthromyalgias, chronic fatigue, and cognitive disorder. Representative features of MMF-associated cognitive dysfunction include attentional dysfunction, dysexecutive syndrome, visual memory deficit and left ear extinction. Our study aims to reevaluate ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.09.019

    authors： Aoun Sebaiti M,Kauv P,Charles-Nelson A,Van Der Gucht A,Blanc-Durand P,Itti E,Gherardi RK,Bachoud-Levi AC,Authier FJ

    更新日期：2018-04-01 00:00:00

  • Comparative solution equilibrium and structural studies of half-sandwich ruthenium(II)(η6-toluene) complexes of picolinate derivatives.

    abstract：:Five Ru(II)(η6-toluene) complexes formed with 2-picolinic acid and its various derivatives have been synthesized and characterized. X-ray structures of four complexes are also reported. Complex formation processes of [Ru(II)(η6-toluene)(H2O)3]2+ organometallic cation with the metal-free ligands were studied in aqueous...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.12.017

    authors： Poljarević JM,Tamás Gál G,May NV,Spengler G,Dömötör O,Savić AR,Grgurić-Šipka S,Enyedy ÉA

    更新日期：2018-04-01 00:00:00

  • Synthesis and evaluation of the antibiotic and adjuvant antibiotic potential of organotin(IV) derivatives.

    abstract：:A series of organotin(IV) derivatives was investigated in vitro for their antibiotic and adjuvant antibiotic properties (efflux pump inhibitors) against Staphylococcus aureus strains that overexpress efflux pump proteins for norfloxacin (SA-1199B), erythromycin (RN-4220) and tetracycline (IS-58). Most organotin(IV) co...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.12.004

    authors： Barbosa ASL,Guedes JS,da Silva DR,Meneghetti SMP,Meneghetti MR,da Silva AE,de Araujo MV,Alexandre-Moreira MS,de Aquino TM,de Siqueira Junior JP,de Araújo RSA,da Cruz RMD,Mendonça-Junior FJB

    更新日期：2018-03-01 00:00:00

  • Relaxation of structural constraints during Amicyanin unfolding.

    abstract：:We study the thermal unfolding of amicyanin by quantifying the resiliency of the native state to structural perturbations. Three signatures characterizing stages of unfolding are identified. The first signature, lateral extension of the polypeptide chain, is calculated directly from the reported crystallographic data....

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.11.016

    authors： Kozak JJ,Gray HB,Garza-López RA

    更新日期：2018-02-01 00:00:00

  • Inclusion complexes between cisplatin and oxidized carbon nanostructures: A theoretical approach.

    abstract：:The toxicity of inclusion compounds formed by carbon nanostructures depends on its functionalized surface, use of solvents, dosage and other properties. Molecular modeling has potentially contributed to the understanding of the chemical nature of the formation of these systems and allows advancement in studies of the ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.10.013

    authors： De Souza LA,Dos Santos HF,Costa LT,De Almeida WB

    更新日期：2018-01-01 00:00:00

  • The influence of the Cys46/Cys55 disulfide bond on the redox and spectroscopic properties of human neuroglobin.

    abstract：:Neuroglobin is a monomeric globin containing a six-coordinate heme b, expressed in the nervous system, which exerts an important neuroprotective role. In the human protein (hNgb), Cys46 and Cys55 form an intramolecular disulfide bond under oxidizing conditions, whose cleavage induces a helix-to-strand rearrangement of...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.10.005

    authors： Bellei M,Bortolotti CA,Di Rocco G,Borsari M,Lancellotti L,Ranieri A,Sola M,Battistuzzi G

    更新日期：2018-01-01 00:00:00

  • Copper transporter 1 in human colorectal cancer cell lines: Effects of endogenous and modified expression on oxaliplatin cytotoxicity.

    abstract：:Oxaliplatin-based chemotherapy is the mainstay for the treatment of advanced colorectal cancer. Copper transporter proteins have been implicated in the transport of platinum-based anticancer drugs, but their expression in human colorectal cancer cell lines and roles in controlling their sensitivity to oxaliplatin are ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.04.022

    authors： Cui H,Zhang AJ,McKeage MJ,Nott LM,Geraghty D,Guven N,Liu JJ

    更新日期：2017-12-01 00:00:00

  • Insights into the recognition and electron transfer steps in nitric oxide reductase from Marinobacter hydrocarbonoclasticus.

    abstract：:Marinobacter hydrocarbonoclasticus nitric oxide reductase, cNOR, is an integral membrane protein composed of two subunits with different roles, NorC (electron transfer) and NorB (catalytic) that receives electrons from the soluble cytochrome c552 and reduces nitric oxide to nitrous oxide in the denitrification pathway...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.09.001

    authors： Ramos S,Almeida RM,Cordas CM,Moura JJG,Pauleta SR,Moura I

    更新日期：2017-12-01 00:00:00

  • Design of silk proteins with increased heme binding capacity and fabrication of silk-heme materials.

    abstract：:In our previous studies, heme was bound into honeybee silk to generate materials that could function as nitric oxide sensors or as recoverable heterogeneous biocatalysts. In this study, we sought to increase the heme-binding capacity of the silk protein by firstly redesigning the heme binding site to contain histidine...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.08.031

    authors： Rapson TD,Liu JW,Sriskantha A,Musameh M,Dunn CJ,Church JS,Woodhead A,Warden AC,Riley MJ,Harmer JR,Noble CJ,Sutherland TD

    更新日期：2017-12-01 00:00:00

  • Controlled self-assembling structures of ferrocene-dipeptide conjugates composed of Ala-Pro-NHCH2CH2SH chain.

    abstract：:Bioorganometallic ferrocene-dipeptide conjugates with the Ala-Pro-cysteamine chain, Fc-L-Ala-L-Pro-NHCH2CH2SH (2) and Fc-L-Ala-D-Pro-NHCH2CH2SH (4) (Fc=ferrocenoyl), were prepared by the reduction of the ferrocene-dipeptide conjugates, Fc-L-Ala-L-Pro-cystamine-L-Pro-L-Ala-Fc (1) or Fc-L-Ala-D-Pro-cystamine-D-Pro-L-Ala...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2017.05.009

    authors： Moriuchi T,Nishiyama T,Tayano Y,Hirao T

    更新日期：2017-12-01 00:00:00

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